Acidic pH conditions induce dissociation of the haem from the protein and destabilise the catalase isolated from Aspergillus terreus

@article{Vatsyayan2010AcidicPC,
  title={Acidic pH conditions induce dissociation of the haem from the protein and destabilise the catalase isolated from Aspergillus terreus},
  author={Preety Vatsyayan and Pranab Goswami},
  journal={Biotechnology Letters},
  year={2010},
  volume={33},
  pages={347-351}
}
The stability (half-life, t½) of the large catalase (CAT) isolated from Aspergillus terreus was decreased under acidic conditions (maximum t½ ~8.5 months at pH ≤ 6) versus alkaline conditions (t½ ~15 months at pH 8–12). Acidic conditions induce the dissociation of haem from CAT, as revealed from a reduction in the Soret peak intensity at 405 nm and an increase in the peak current at Fe3+/Fe2+ redox potentials. This increase in current is attributed to the facile electron transfer from the free… CONTINUE READING

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