Acidic infusion in early reperfusion affects the activity of antioxidant enzymes in postischemic isolated rat heart.

@article{Penna2013AcidicII,
  title={Acidic infusion in early reperfusion affects the activity of antioxidant enzymes in postischemic isolated rat heart.},
  author={Claudia Penna and Maria-Giulia Perrelli and Francesca Tullio and Carmelina Angotti and Pasquale Pagliaro},
  journal={The Journal of surgical research},
  year={2013},
  volume={183 1},
  pages={111-8}
}
BACKGROUND Acidic perfusion (AP) performed at the onset of reperfusion (i.e., acid postconditioning) is cardioprotective. We investigated the effect of AP on postischemic cardiac function and on the activity of endogenous superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase. The role of exogenous CAT or SOD on AP cardioprotection was also investigated. Phosphorylation of redox-sensitive survival kinases (protein kinase C [PKC] ε and extracellular signal-regulated kinase [ERK… CONTINUE READING

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American journal of physiology. Heart and circulatory physiology • 2007
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