Acidic fibroblast growth factor promotes vascular repair.

  title={Acidic fibroblast growth factor promotes vascular repair.},
  author={Thorir D. Bjornsson and Maciej L. Dryjski and J P Tluczek and R J Mennie and John Ronan and Theodore N. Mellin and Kenneth A. Thomas},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  volume={88 19},
Intravascular injury to arteries can result in thickening of the intimal smooth muscle layer adjacent to the lumen by migration and proliferation of cells from the underlying medial smooth muscle layer accompanied by deposition of extracellular matrix. This pathological response, which decreases lumen diameter, might, in part, be the result of the access of smooth muscle cells to plasma and platelet-derived growth factors as a consequence of denudation of the overlying confluent monolayer of… CONTINUE READING


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