Acidic and basic fibroblast growth factor mRNAs are increased in striatum following MPTP-induced dopamine neurofiber lesion: assay by quantitative PCR.

@article{Leonard1993AcidicAB,
  title={Acidic and basic fibroblast growth factor mRNAs are increased in striatum following MPTP-induced dopamine neurofiber lesion: assay by quantitative PCR.},
  author={Stephen Leonard and D Luthman and J. D. Logel and Johan Luthman and C M Antle and Robert Freedman and Barry L. Hoffer},
  journal={Brain research. Molecular brain research},
  year={1993},
  volume={18 4},
  pages={275-84}
}
Acidic fibroblast growth factor (aFGF) and basic fibroblast growth factor (bFGF), the two best characterized members of a growing family of heparin-binding growth factors, have been shown to affect both survival of cultured neurons and regeneration of nerve terminals when applied exogenously. The endogenous expression of these growth factors in response to brain injury is not well understood. We have utilized the Swiss-Webster mouse, treated with the neurotoxin 1-methyl-4-phenyl-1,2,3,6… CONTINUE READING

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