Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors

@article{Foster1984AcidicAA,
  title={Acidic amino acid binding sites in mammalian neuronal membranes: their characteristics and relationship to synaptic receptors},
  author={A. Foster and G. Fagg},
  journal={Brain Research Reviews},
  year={1984},
  volume={7},
  pages={103-164}
}
  • A. Foster, G. Fagg
  • Published 1984
  • Biology, Medicine
  • Brain Research Reviews
  • This review summarizes studies designed to label and characterize mammalian synaptic receptors for glutamate, aspartate and related acidic amino acids using in vitro ligand binding techniques. The binding properties of the 3 major ligands employed--L-[3H]glutamate, L-[3H]aspartate and [3H]kainate--are described in terms of their kinetics, the influence of ions, pharmacology, molecular nature, localization and physiological/pharmacological function. In addition, the binding characteristics are… CONTINUE READING
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    Chapter 10 Glutamate receptors

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