Acid-stable low molecular mass proteinase inhibitors in human lung lavage.

@article{Smith1986AcidstableLM,
  title={Acid-stable low molecular mass proteinase inhibitors in human lung lavage.},
  author={Stephanie F Smith and Abraham Guz and G. H. Burton and Nigel T Cooke and Teresa D. Tetley},
  journal={Biological chemistry Hoppe-Seyler},
  year={1986},
  volume={367 3},
  pages={183-9}
}
An acid-stable, low molecular mass proteinase inhibitor, bronchial mucus proteinase inhibitor (BMPI), has been isolated from sputum and partially characterised. A single band with a modal molecular mass of 18 700 was observed following SDS-polyacrylamide gel electrophoresis. BMPI inhibited human leukocyte elastase, cathepsin G, trypsin and chymotrypsin, but not porcine pancreatic elastase. Although BMPI had a molecular mass close to the similarly isolated inhibitor of Girard et al. (Girard, F… CONTINUE READING