Acid sensing by sweet and bitter taste neurons in Drosophila melanogaster

@inproceedings{Charlu2013AcidSB,
  title={Acid sensing by sweet and bitter taste neurons in Drosophila melanogaster},
  author={Sandhya Charlu and Zev Wisotsky and Adriana Medina and Anupama Dahanukar},
  booktitle={Nature communications},
  year={2013}
}
Drosophila melanogaster can taste various compounds and separate them into few basic categories such as sweet, bitter and salt taste. Here we investigate mechanisms underlying acid detection in Drosophila and report that the fly displays strong taste aversion to common carboxylic acids. We find that acid tastants act by the activation of a subset of bitter neurons and inhibition of sweet neurons. Bitter neurons begin to respond at pH 5 and show an increase in spike frequency as the… CONTINUE READING
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