Acid phosphatase isozymes in cancer of the prostate.

@article{Reif1973AcidPI,
  title={Acid phosphatase isozymes in cancer of the prostate.},
  author={Arnold E. Reif and R M Schlesinger and C A Fish and Charles Marshall Robinson},
  journal={Cancer},
  year={1973},
  volume={31 3},
  pages={
          689-99
        }
}
Acid phosphatase (AP-ase) isozymes were studied in prostatic carcinoma, to determine to what extent they remain active and unchanged. In contrast to serum AP-ase, that of tissue homogenates was relatively stable. Tartrate-sensitive AP-ase activity varied 100-fold for lesions taken from 11 different patients, without complete loss of activity in any lesion. The results explain why the serum AP-ase activity is not invariably elevated even in patients with metastatic cancer of the prostate. An… CONTINUE READING

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