Corpus ID: 13603750

Acid phosphatase activity in senile plaques and cerebrospinal fluid of patients with Alzheimer's disease.

@article{Omar1993AcidPA,
  title={Acid phosphatase activity in senile plaques and cerebrospinal fluid of patients with Alzheimer's disease.},
  author={R. Omar and M. Pappolla and I. Argani and K. Davis},
  journal={Archives of pathology & laboratory medicine},
  year={1993},
  volume={117 2},
  pages={
          166-9
        }
}
  • R. Omar, M. Pappolla, +1 author K. Davis
  • Published 1993
  • Biology, Medicine
  • Archives of pathology & laboratory medicine
  • The origin of the various components of senile plaques in Alzheimer's disease (AD) continues to be a focus of intense research scrutiny. Lysosomal enzyme activity within the plaques is of particular interest because of its possible relevance to a presumed abnormal processing of precursor molecules that may lead to the formation of plaque amyloid. Histochemical evidence of acid phosphatase (ACP), a lysosomal hydrolase, activity in senile plaques has been documented long before many of the… CONTINUE READING
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