Acid phosphatase: new developments.

  title={Acid phosphatase: new developments.},
  author={Nicholas A. Romas and Noel R. Rose and Myron Tannenbaum},
  journal={Human pathology},
  volume={10 5},
Acid phosphatase was the first "tumor marker" to be measured in the blood, and over 40 years have passed since an elevation of the serum acid phosphatase level was observed in patients with prostatic carcinoma. However, significant elevations in the level of this enzyme have been observed in other diseases, as well as elevations of other tissue phosphatases. Many improvements in the colorimetric technique have been introduced, but none has been used successfully to detect the tissue origin of… CONTINUE READING