Acid-base and endocrine effects of aldosterone and angiotensin II inhibition in metabolic acidosis in human patients.

@article{Henger2000AcidbaseAE,
  title={Acid-base and endocrine effects of aldosterone and angiotensin II inhibition in metabolic acidosis in human patients.},
  author={A Henger and P W Tutt and Walter F. Riesen and Henry N Hulter and Reto Krapf},
  journal={The Journal of laboratory and clinical medicine},
  year={2000},
  volume={136 5},
  pages={379-89}
}
Chronic metabolic acidosis (CMA) in human beings is characterized by increased renin-angiotensin-aldosterone (RAA) activity and cortisol secretion as well as nitrogen wasting. The purpose of this study was to examine whether and to what extent increased RAA activity (i.e., angiotensin II or aldosterone) regulates acid-base equilibrium in CMA and thus might… CONTINUE READING