Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring.

@article{Mainie2006AcidAN,
  title={Acid and non-acid reflux in patients with persistent symptoms despite acid suppressive therapy: a multicentre study using combined ambulatory impedance-pH monitoring.},
  author={Inder Mohan Lal Mainie and Radu I. Tutuian and Scott Shay and Milagros Vela and Xiaodong Zhang and Daniel A Sifrim and D. Castell},
  journal={Gut},
  year={2006},
  volume={55 10},
  pages={1398-402}
}
BACKGROUND AND AIMS Empiric proton pump inhibitor (PPI) trials have become increasingly popular leading to gastroenterologists frequently evaluating gastro-oesophageal reflux disease (GORD) patients only after they have "failed" PPI therapy. Combined multichannel intraluminal impedance and pH (MII-pH) monitoring has the ability to detect gastro-oesophageal reflux (GOR) episodes independent of their pH and evaluate the relationship between symptoms and all types of GOR. Using this technique, we… CONTINUE READING
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