Acid-Suppressing Agents and Risk for Clostridium difficile Infection in Pediatric Patients.

@article{Brown2015AcidSuppressingAA,
  title={Acid-Suppressing Agents and Risk for Clostridium difficile Infection in Pediatric Patients.},
  author={Katelyn E. Brown and Chad A. Knoderer and Kristen R. Nichols and Ashley S Crumby},
  journal={Clinical pediatrics},
  year={2015},
  volume={54 11},
  pages={1102-6}
}
BACKGROUND Acid-suppressing agents have been associated with increased Clostridium difficile infection (CDI) in adults. The objective of this study was to evaluate the association of acid-suppressing therapy with the development of CDI in the pediatric population. METHODS This was a retrospective case-control study. Children aged 1 through 17 years with a positive C difficile polymerase chain reaction (PCR) result obtained between June 1, 2008, and June 1, 2012, were randomly matched to a… CONTINUE READING