Achromobacter species in cystic fibrosis: cross-infection caused by indirect patient-to-patient contact.

Abstract

BACKGROUND AND METHODS Achromobacter species leads to chronic infection in an increasing number of CF patients. We report 2 cases of Achromobacter ruhlandii cross-infection between patients after well-described indirect contact. RESULTS Both cases were young, stable, CF patients without chronic infections and with normal FEV1, but experienced clinical deterioration after visits to the home of a CF patient with A. ruhlandii infection and after sharing facilities with an A. ruhlandii infected CF patient on a skiing vacation, respectively. Both cases became positive for A. ruhlandii in airway secretions and were colonized with A. ruhlandii in their sinuses. Aggressive, long-term antibiotic treatment led to clinical stability. One of the cases developed chronic A. ruhlandii infection. CONCLUSION A. species can cause cross-infection even after a short period of indirect contact between infected and non-infected CF patients. Patients should be followed closely for several months before the possibility of cross-infection is ruled out.

DOI: 10.1016/j.jcf.2013.05.004

Cite this paper

@article{Hansen2013AchromobacterSI, title={Achromobacter species in cystic fibrosis: cross-infection caused by indirect patient-to-patient contact.}, author={Christine R\onne Hansen and Tacjana Pressler and Winnie Ridderberg and Helle Krogh Johansen and Marianne Nielsine Skov}, journal={Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society}, year={2013}, volume={12 6}, pages={609-15} }