Achieving ultrasensitive in vivo detection of bone crack with polydopamine-capsulated surface-enhanced Raman nanoparticle.

@article{Jiang2017AchievingUI,
  title={Achieving ultrasensitive in vivo detection of bone crack with polydopamine-capsulated surface-enhanced Raman nanoparticle.},
  author={Chunhuan Jiang and Ying Wang and Jiawei Wang and Wei Song and Lehui Lu},
  journal={Biomaterials},
  year={2017},
  volume={114},
  pages={54-61}
}
The timely diagnosis and intervention of bone microdamage are essential for preventing its accumulation and further diminishing the risk of skeletal fracture. Although staining methods have been adopted to better depict the microdamage on bone, their clinical impacts are still limited because they are based on histological sections which are inherently… CONTINUE READING