Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center study: the DISCOVERY-Beta study

@article{Laks2008AchievingLG,
  title={Achieving lipid goals with rosuvastatin compared with simvastatin in high risk patients in real clinical practice: a randomized, open-label, parallel-group, multi-center study: the DISCOVERY-Beta study},
  author={Toivo Laks and Ester Keba and Mariann Leiner and Eero Merilind and Mall Petersen and Sirje Reinmets and Sille V{\"a}li and Terje S{\"o}{\"o}t and Karin Otter},
  journal={Vascular Health and Risk Management},
  year={2008},
  volume={4},
  pages={1407 - 1416}
}
The aim of this multi-center, open-label, randomized, parallel-group trial was to compare the efficacy of rosuvastatin with that of simvastatin in achieving the 1998 European Atherosclerosis Society (EAS) lipid treatment goals. 504 patients (> or =18 years) with primary hypercholesterolemia and a 10-year cardiovascular (CV) risk >20% or history of coronary heart disease (CHD) or other established atherosclerotic disease were randomized in a 2:1 ratio to receive rosuvastatin 10 mg or simvastatin… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 39 references

Task Force Report: Prevention of coronary heart disease in clinical practice. Recommendations of the Second Joint Task Force of European and Other Societies on coronary prevention

  • D Wood, G De Backer, O Faegerman
  • Eur Heart J,
  • 1998
Highly Influential
4 Excerpts

Achieving lipid goals in real life: the DISCOVERY-UK study

  • A Middleton, A. Fuat
  • Br J Cardiol, 13:72–6.
  • 2006
2 Excerpts

DISCOVERY BELUX: An open-label, randomised, multi-centre, phase IIIb, parallel group study

  • MC Herregods, JC Daubresse, G Michel
  • 2006
2 Excerpts

Direct statin comparison of LDL - C values : an evaluation of rosuvastatin therapy ( DISCOVERY – Canada ) . [ abstract ]

  • MC Herregods, JC Daubresse, G Michel
  • 2005

Direct statin comparison of LDL-C values: an evaluation of rosuvastatin therapy (DISCOVERY – Canada)

  • M Gupta, C. Constance
  • [abstract]. Atheroscler Suppl, 6:108.
  • 2005
2 Excerpts

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