Achieving global perfect homeostasis through transporter regulation


Nutrient homeostasis-the maintenance of relatively constant internal nutrient concentrations in fluctuating external environments-is essential to the survival of most organisms. Transcriptional regulation of plasma membrane transporters by internal nutrient concentrations is typically assumed to be the main mechanism by which homeostasis is achieved. While… (More)
DOI: 10.1371/journal.pcbi.1005458

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