Achieving efficient delivery of morpholino oligos in cultured cells.

@article{Morcos2001AchievingED,
  title={Achieving efficient delivery of morpholino oligos in cultured cells.},
  author={Paul A. Morcos},
  journal={Genesis},
  year={2001},
  volume={30 3},
  pages={94-102}
}
One of the many features that make morpholino oligos unique among the antisense structural types is an uncharged backbone. While this feature eliminates the nonspecific interactions of traditional S-oligos, it also renders the morpholino undeliverable via the traditional lipid-based delivery systems. This article describes a highly efficient method of delivering morpholino oligos into adherent and nonadherent cultured cells. In this system, a nonionic morpholino oligo is paired to a… CONTINUE READING

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