Achalasia: a new clinically relevant classification by high-resolution manometry.

@article{Pandolfino2008AchalasiaAN,
  title={Achalasia: a new clinically relevant classification by high-resolution manometry.},
  author={John E. Pandolfino and Monika A. Kwiatek and Thomas B Nealis and William J. Bulsiewicz and Jennifer Post and Peter J. Kahrilas},
  journal={Gastroenterology},
  year={2008},
  volume={135 5},
  pages={1526-33}
}
BACKGROUND & AIMS Although the diagnosis of achalasia hinges on demonstrating impaired esophagogastric junction (EGJ) relaxation and aperistalsis, 3 distinct patterns of aperistalsis are discernable with high-resolution manometry (HRM). This study aimed to compare the clinical characteristics and treatment response of these 3 subtypes. METHODS One thousand clinical HRM studies were reviewed, and 213 patients with impaired EGJ relaxation were identified. These were categorized into 4 groups… CONTINUE READING
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