Acetylsalicylic acid and montelukast block mast cell mediator-related symptoms during rapid desensitization.

@article{Breslow2009AcetylsalicylicAA,
  title={Acetylsalicylic acid and montelukast block mast cell mediator-related symptoms during rapid desensitization.},
  author={Rebecca G. Breslow and Joana Caiado and Mariana C. Castells},
  journal={Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology},
  year={2009},
  volume={102 2},
  pages={155-60}
}
BACKGROUND Rapid desensitization is a process in which drug-allergic patients receive their target dose in incremental steps, resulting in a state of temporary tolerization. In this manner, first-line therapy can be delivered safely, even in patients who present with severe hypersensitivity reactions (HSRs) to the given agent. A small subset of patients has persistent HSRs during rapid desensitization that can be refractory to antihistamines and corticosteroids. OBJECTIVE To increase the… CONTINUE READING
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