Acetylcholinesterases--the structural similarities and differences.

@article{Wiesner2007AcetylcholinesterasestheSS,
  title={Acetylcholinesterases--the structural similarities and differences.},
  author={Jiri Wiesner and Zdenek Kr{\'i}z and Kamil Ku{\vc}a and Daniel Jun and Jaroslav Ko{\vc}a},
  journal={Journal of enzyme inhibition and medicinal chemistry},
  year={2007},
  volume={22 4},
  pages={
          417-24
        }
}
Acetylcholinesterase (AChE) is a widely spread enzyme playing a very important role in nerve signal transmission. As AChE controls key processes, its inhibition leads to the very fast death of an organism, including humans. However, when this feature is to be used for killing of unwanted organisms (i.e. mosquitoes), one is faced with the question - how much do AChEs differ between species and what are the differences? Here, a theoretical point of view was utilized to identify the structural… CONTINUE READING

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