Acetylcholinesterase-inhibiting activity of salicylanilide N-alkylcarbamates and their molecular docking.

@article{Imramovsk2012AcetylcholinesteraseinhibitingAO,
  title={Acetylcholinesterase-inhibiting activity of salicylanilide N-alkylcarbamates and their molecular docking.},
  author={Ale{\vs} Imramovsk{\'y} and {\vS}{\'a}rka {\vS}těp{\'a}nkov{\'a} and J{\'a}n Van{\vc}o and Karel Pauk and Juana Monreal-Ferriz and Jarmila Vin{\vs}ov{\'a} and Josef Jamp{\'i}lek},
  journal={Molecules},
  year={2012},
  volume={17 9},
  pages={10142-58}
}
A series of twenty-five novel salicylanilide N-alkylcarbamates were investigated as potential acetylcholinesterase inhibitors. The compounds were tested for their ability to inhibit acetylcholinesterase (AChE) from electric eel (Electrophorus electricus L.). Experimental lipophilicity was determined, and the structure-activity relationships are discussed… CONTINUE READING