Acetylcholinesterase Activity in Eserine-treated Ascidian Embryos.

  title={Acetylcholinesterase Activity in Eserine-treated Ascidian Embryos.},
  author={David Fromson and J. R. Whittaker},
  journal={The Biological bulletin},
  volume={139 2},
1. The use of specific cholinesterase inhibitors and substrates demonstrated that the enzyme activity in Ciona intestinalis larvae is an acetylcholinesterase. 2. Eggs treated with eserine sulfate (an acetylcholinesterase inhibitor) for one hour prior to fertilization developed into larvae with defective muscular movements and greatly reduced levels of acetylcholinesterase activity. 3. Two kinds of experiments show that this reduced enzyme activity was caused by the retention of eserine and not… CONTINUE READING