Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish

@inproceedings{Shi2014AcetylcholineSA,
  title={Acetylcholine serves as a derepressor in Loperamide-induced Opioid-Induced Bowel Dysfunction (OIBD) in zebrafish},
  author={Yanyan Shi and Yu Zhang and Fangying Zhao and Hua Ruan and Honghui Huang and Lingfei Luo and Lin Li},
  booktitle={Scientific reports},
  year={2014}
}
The mechanisms underlying gut development, especially peristalsis, are widely studied topics. However, the causes of gut peristalsis-related diseases, especially Opioid-Induced Bowel Dysfunction (OIBD) disorder, have not been well defined. Therefore, our study used zebrafish, a popular model for studying both gut development and peristalsis, and DCFH-DA, a dye that clearly labels the live fish gut lumen, to characterize the formation process of gut lumen as well as the gut movement style in… CONTINUE READING
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