Acetylcholine receptor-reactive T cells in myasthenia gravis: evidence for the involvement of different subpopulations of T helper cells.

@article{Yi1994AcetylcholineRT,
  title={Acetylcholine receptor-reactive T cells in myasthenia gravis: evidence for the involvement of different subpopulations of T helper cells.},
  author={Qi-long Yi and Richard Ahlberg and Ritva Pirskanen and Ann Kari Lefvert},
  journal={Journal of neuroimmunology},
  year={1994},
  volume={50 2},
  pages={177-86}
}
Patients with myasthenia gravis have a high prevalence of acetylcholine receptor-specific T lymphocytes in the peripheral blood. Our earlier study shows that these T lymphocytes are stimulated to secrete interferon (IFN)-gamma and interleukin (IL)-2 in response to the autoantigen. Such stimulated T cells may be subdivided into different subsets according to the pattern of cytokine production. In the present study we have investigated the subpopulations of cells by analyzing their IL-4, IFN… CONTINUE READING