Acetylcholine receptor degradation measured by pulse chase labelling

Abstract

THERE is increasing evidence that the turnover of the cholinergic receptor protein in developing or adult muscle fibres varies in the course of synaptogenesis or as a consequence of denervation1,2. Muscle activity is involved in this regulation3, but the mechanisms of the control processes and the chemical signals which mediate these effects remain largely… (More)
DOI: 10.1038/264074a0

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