Acetylcholine receptor agonists stimulate [3H]taurine release from rat sympathetic ganglia.

  title={Acetylcholine receptor agonists stimulate [3H]taurine release from rat sympathetic ganglia.},
  author={Robert A. Waniewski and D. L. Martin},
  journal={European journal of pharmacology},
  volume={260 2-3},
3 Citations

Nicotinic receptors mediate the release of amino acid neurotransmitters in cultured cortical neurons.

Nicotine stimulation of cortical neurons obtained from gestation day 19 rats provoked a dose-dependent release of aspartate, glutamate, glycine and GABA, indicating a functional role for the nicotinic receptor in this model, and it was shown that L, N, and P/Q type Ca2+ channels are involved in nicotine-mediatedCa2+ entry into cortical neurons.



A modulating role of taurine on release of acetylcholine and norepinephrine from neuronal tissues.

The results suggest that taurine may act as a modulator of neuronal activity, possibly by stabilizing excitable membrane and by suppressing the release of neurotansmitter at synapses.

Adenosine stimulates cAMP‐mediated taurine release from LRM55 glial cells

Results indicate that, in addition to directly affecting neurons, adenosine may have a primary site of action on astroglial cells resulting in taurine release and subsequent inhibition of neuronal activity.

[3H]gamma‐Aminobutyric acid uptake into neuroglial cells of rat superior cervical sympathetic ganglia.

Calculations of net fluxes from unidirectional tracer fluxes suggest that the sympathetic glial cells are capable of promoting net uptake of GABA at external concentrations above 1 microM.

Tachykinin‐Stimulated Inositol Phospholipid Hydrolysis and Taurine Release from Human Astrocytoma Cells

Findings are consistent with the hypothesis that an activation of NK1 receptors on U373 MG cells results in the release of inositol phosphates and activation of PKC, which in turn may regulate therelease of taurine.

Isoproterenol selectively releases endogenous and [14C]‐labelled taurine from a single cytosolic compartment in astroglial cells

Taurine compartmentation was examined and measurements of the specific radioactivity of taurine indicate that accumulated [14C]taurine mixes homogeneously with endogenous tauriine and both are simultaneously released from the same pool.

Release of Endogenous Taurine and γ‐Aminobutyric Acid from Brain Slices from the Adult and Developing Mouse

The results suggest that taurine may be an important regulator of excitability in the developing brain.