Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling.

@article{Kistemaker2015AcetylcholineBB,
  title={Acetylcholine beyond bronchoconstriction: roles in inflammation and remodeling.},
  author={Loes E M Kistemaker and Reinoud Gosens},
  journal={Trends in pharmacological sciences},
  year={2015},
  volume={36 3},
  pages={164-71}
}
Acetylcholine is the primary parasympathetic neurotransmitter in the airways, where it not only induces bronchoconstriction and mucus secretion, but also regulates airway inflammation and remodeling. In this review, we propose that these effects are all primarily mediated via the muscarinic M3 receptor. Acetylcholine promotes inflammation and remodeling via… CONTINUE READING