Acetylation of fluoroquinolone antimicrobial agents by an Escherichia coli strain isolated from a municipal wastewater treatment plant.

@article{Jung2009AcetylationOF,
  title={Acetylation of fluoroquinolone antimicrobial agents by an Escherichia coli strain isolated from a municipal wastewater treatment plant.},
  author={Carina M Jung and Thomas M. Heinze and Ruth Strakosha and C. A. Elkins and John B. Sutherland},
  journal={Journal of applied microbiology},
  year={2009},
  volume={106 2},
  pages={
          564-71
        }
}
AIMS To isolate environmental bacteria capable of transforming fluoroquinolones to inactive molecules. METHODS AND RESULTS Bacteria were isolated from the aerobic liquor of a wastewater treatment plant on a medium containing norfloxacin (100 mg l(-1)). Twenty-two isolates were highly resistant (minimal inhibitory concentration: 6.25-200 microg ml(-1)) to five fluoroquinolones and six of them were positive by PCR amplification for the aminoglycoside resistance gene aac(6')-Ib. Of these, only… CONTINUE READING

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