Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer

Abstract

Chromatin-based DNA damage response (DDR) pathways are fundamental for preventing genome and epigenome instability, which are prevalent in cancer. Histone acetyltransferases (HATs) and histone deacetylases (HDACs) catalyze the addition and removal of acetyl groups on lysine residues, a post-translational modification important for the DDR. Acetylation can… (More)
DOI: 10.1371/journal.pgen.1006272

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Cite this paper

@inproceedings{Gong2016AcetylationRP, title={Acetylation Reader Proteins: Linking Acetylation Signaling to Genome Maintenance and Cancer}, author={Fade Gong and Li-Ya Chiu and Kyle M Miller}, booktitle={PLoS genetics}, year={2016} }