Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects

@article{Martinotti2011AcetyllCarnitineIT,
  title={Acetyl-l-Carnitine in the treatment of anhedonia, melancholic and negative symptoms in alcohol dependent subjects},
  author={Giovanni Martinotti and Sara Andreoli and Daniela Reina and Marco Di Nicola and Luigi Janiri Prof},
  journal={Progress in Neuro-Psychopharmacology and Biological Psychiatry},
  year={2011},
  volume={35},
  pages={953-958}
}
OBJECTIVE Aim of this randomized, double-blind, placebo-controlled study was to evaluate the efficacy of Acetyl-l-Carnitine (ALC), at different dosages, on specific anhedonic symptoms in detoxified alcohol dependent subjects. Secondary endpoints were the effect of ALC on melancholic and negative symptoms. METHOD Sixty-four anhedonic alcohol dependent patients with minor or absent withdrawal symptoms were randomized: 23 received ALC at a dosage of 3g/day, 21 received ALC at a dosage of 1g/day… CONTINUE READING
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