Acetyl-L-carnitine (ALC) administration positively affects reproductive axis in hypogonadotropic women with functional hypothalamic amenorrhea.

@article{Genazzani2011AcetylLcarnitineA,
  title={Acetyl-L-carnitine (ALC) administration positively affects reproductive axis in hypogonadotropic women with functional hypothalamic amenorrhea.},
  author={Alessandro David Genazzani and Chiara Lanzoni and Federica Ricchieri and Susanna Santagni and Erika Rattighieri and Elisa Chierchia and Palmiero Monteleone and Valerio Maria Jasonni},
  journal={Journal of endocrinological investigation},
  year={2011},
  volume={34 4},
  pages={287-91}
}
BACKGROUND Hypothalamic amenorrhea (HA) is characterized by neuroendocrine impairment that, in turn, negatively modulates endocrine function, mainly within the reproductive axis. HA presents with hypo-LH, hypoestrogenism and, until now, a definite therapeutic strategy has not yet been found. The aim of the following study was to test the efficacy of acetyl-L-carnitine (ALC) administration in HA-affected subjects. POPULATION Twenty-four patients affected by stress-induced HA were divided into… CONTINUE READING