Acetyl Cysteine as a Glutathione Precursor for chizophrenia — A Double-Blind , Randomized , lacebo-Controlled Trial

@inproceedings{Berk2008AcetylCA,
  title={Acetyl Cysteine as a Glutathione Precursor for chizophrenia — A Double-Blind , Randomized , lacebo-Controlled Trial},
  author={I. v.d. Berk and David Leon Copolov and Olivia M Dean and Kristy Lu and Sue Jeavons and Ian Schapkaitz and urray Anderson-Hunt and Frank W. Judd and Fiona Katz and Paul R. Katz and Sean Ording-Jespersen and J. Little and hilippe Conus and M. Cu{\'e}nod and Kim Q Do and Ashley I. Bush},
  year={2008}
}
ackground: Brain glutathione levels are decreased in schizophrenia, a disorder that often is chronic and refractory to treatment. N-acetyl ysteine (NAC) increases brain glutathione in rodents. This study was conducted to evaluate the safety and effectiveness of oral NAC (1 g rally twice daily [b.i.d.]) as an add-on to maintenance medication for the treatment of chronic schizophrenia over a 24-week period. 

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