Acetazolamide improves oxygenation in patients with respiratory failure and metabolic alkalosis.

@article{Gulsvik2013AcetazolamideIO,
  title={Acetazolamide improves oxygenation in patients with respiratory failure and metabolic alkalosis.},
  author={Ragnhild Gulsvik and Ingunn Skj{\o}rten and Kenneth Undhjem and Lars Hol{\o} and Anne Frostad and Eirunn Waatevik Saure and Vasvija Lejlic and Sjur Humerfelt and Gunnar Hansen and Torgeir Bruun Wyller},
  journal={The clinical respiratory journal},
  year={2013},
  volume={7 4},
  pages={
          390-6
        }
}
INTRODUCTION Coexistent respiratory failure and metabolic alkalosis is a common finding. Acidotic diuretics cause a fall in pH that may stimulate respiration. OBJECTIVE The purpose of the study was to evaluate the effectiveness of short-term treatment with acetazolamide for combined respiratory failure and metabolic alkalosis. METHODS A randomised, placebo-controlled and double-blind parallel group trial where oral acetazolamide 250 mg three times a day for 5 days were administered to… CONTINUE READING
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