Acetate Kinase Isozymes Confer Robustness in Acetate Metabolism

@inproceedings{Chan2014AcetateKI,
  title={Acetate Kinase Isozymes Confer Robustness in Acetate Metabolism},
  author={Siu Hung Joshua Chan and Lasse Benn N\orregaard and Christian Solem and Peter Ruhdal Jensen},
  booktitle={PloS one},
  year={2014}
}
Acetate kinase (ACK) (EC no: 2.7.2.1) interconverts acetyl-phosphate and acetate to either catabolize or synthesize acetyl-CoA dependent on the metabolic requirement. Among all ACK entries available in UniProt, we found that around 45% are multiple ACKs in some organisms including more than 300 species but surprisingly, little work has been done to clarify whether this has any significance. In an attempt to gain further insight we have studied the two ACKs (AckA1, AckA2) encoded by two… CONTINUE READING

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JH Miller
New York (US): Cold Spring Harbor Laboratory • 1972
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