Acetaminophen normalizes glucose homeostasis in mouse models for diabetes.


Loss of pancreatic beta cell insulin secretion is the most important element in the progression of type 1 and type 2 diabetes. Since oxidative stress is involved in the progressive loss of beta cell function, we evaluated the potential for the over-the-counter analgesic drug and antioxidant, acetaminophen (APAP), to intervene in the diabetogenic process. We… (More)
DOI: 10.1016/j.bcp.2007.12.003


Cite this paper

@article{Shertzer2008AcetaminophenNG, title={Acetaminophen normalizes glucose homeostasis in mouse models for diabetes.}, author={Howard G. Shertzer and Scott Schneider and Eric L Kendig and Deborah J. Clegg and David A D'Alessio and Mary Beth Genter}, journal={Biochemical pharmacology}, year={2008}, volume={75 6}, pages={1402-10} }