Acetaminophen hepatotoxicity: an updated review

@article{Lancaster2014AcetaminophenHA,
  title={Acetaminophen hepatotoxicity: an updated review},
  author={Elizabeth M. Lancaster and J. Hiatt and A. Zarrinpar},
  journal={Archives of Toxicology},
  year={2014},
  volume={89},
  pages={193-199}
}
As the most common cause of acute liver failure (ALF) in the USA and UK, acetaminophen-induced hepatotoxicity remains a significant public health concern and common indication for emergent liver transplantation. This problem is largely attributable to acetaminophen combination products frequently prescribed by physicians and other healthcare professionals, with unintentional and chronic overdose accounting for over 50 % of cases of acetaminophen-related ALF. Treatment with N-acetylcysteine can… Expand
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