author={Ibrahim Altabakhi and P. Zito},
The FDA recognized the combination of acetylsalicylic acid (250 mg), acetaminophen (250 mg), and caffeine (65 mg) as safe and effective in treating acute headaches, especially migraine, and was considered effective also by the American Headache Society (Level A). This combination is well-tolerated in episodic tension-type headache and considered superior to acetaminophen. All components of this combination are considered safe during breastfeeding and can be taken orally for acute migraine… Expand