Acetaldehyde-Reinforcing Effects: A Study on Oral Self-Administration Behavior

@inproceedings{Peana2010AcetaldehydeReinforcingEA,
  title={Acetaldehyde-Reinforcing Effects: A Study on Oral Self-Administration Behavior},
  author={Alessandra Tiziana Peana and Giulia Muggironi and Marco Diana},
  booktitle={Front. Psychiatry},
  year={2010}
}
Acetaldehyde (ACD) is the first metabolite of ethanol. Although, the role of ACD in ethanol addiction has been controversial, there are data showing a relationship. The objective of the current study was to further test the hypothesis that ACD itself is reinforcing. For this reason, we carried out a study on operant oral ACD self-administration. Wistar rats were trained to self-administer tap water or ACD by nose-poking in daily 30 min sessions for 15 consecutive days. Response on active nose… CONTINUE READING
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