Acetaldehyde-Reinforcing Effects: A Study on Oral Self-Administration Behavior

  title={Acetaldehyde-Reinforcing Effects: A Study on Oral Self-Administration Behavior},
  author={Alessandra Tiziana Peana and Giulia Muggironi and Marco Diana},
  booktitle={Front. Psychiatry},
Acetaldehyde (ACD) is the first metabolite of ethanol. Although, the role of ACD in ethanol addiction has been controversial, there are data showing a relationship. The objective of the current study was to further test the hypothesis that ACD itself is reinforcing. For this reason, we carried out a study on operant oral ACD self-administration. Wistar rats were trained to self-administer tap water or ACD by nose-poking in daily 30 min sessions for 15 consecutive days. Response on active nose… CONTINUE READING
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Acute effects of naltrexone and GBR 12909 on ethanol drinking-in-the-dark in C57BL/6J mice

  • S.J.
  • Psychopharmacology 192, 207–217.
  • 2007
Highly Influential
12 Excerpts

Environmental modulation of alcohol self-administration in the rat

  • A. Testa, A. Badiani
  • Neuroscience. Program/Poster: 564.26/ II2. http…
  • 2008
Highly Influential
2 Excerpts

The Peripheral Competitive Inhibitor of Alcohol Dehydrogenase

  • A. T. Peana, A. R. Assaretti, G. Muggironi, P. Enrico, M. Diana
  • 2008
Highly Influential
4 Excerpts

Acetaldehyde-reinforcing effects: a study on oral self-administration behavior. Front. Psychiatry 1:23

  • AT Citation Peana, G Muggironi, M Diana
  • 2010
1 Excerpt

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