Acetaldehyde Content and Oxidative Stress in the Deleterious Effects of Alcohol Drinking on Rat Uterine Horn

@inproceedings{Buthet2013AcetaldehydeCA,
  title={Acetaldehyde Content and Oxidative Stress in the Deleterious Effects of Alcohol Drinking on Rat Uterine Horn},
  author={Lara Romina Buthet and Mar{\'i}a Eugenia Maciel and Leandro N{\'e}stor Quintans and Carmen Rodr{\'i}guez de Castro and Mart{\'i}n Hern{\'a}n Costantini and Silvia Laura Fanelli and Jos{\'e} Alberto de Castro and Gerardo Daniel Castro},
  booktitle={Journal of toxicology},
  year={2013}
}
After alcohol exposure through a standard Lieber and De Carli diet for 28 days, a severe atrophy in the rat uteirne horn was observed, accompanied by significant alterations in its epithelial cells. Microsomal pathway of acetaldehyde production was slightly increased. Hydroxyl radicals were detected in the cytosolic fraction, and this was attributed to participation of xanthine oxidoreductase. They were also observed in the microsomal fraction in the presence of NADPH generating system. No… CONTINUE READING