Acetabular Protrusion in Osteogenesis Imperfecta

  title={Acetabular Protrusion in Osteogenesis Imperfecta},
  author={Philippe Violas and François Fassier and Reggie C Hamdy and Morris Duhaime and Francis H Glorieux},
  journal={Journal of Pediatric Orthopaedics},
The charts and radiographs of 79 patients with osteogenesis imperfecta (OI) actively followed at the authors' institution were reviewed to determine the incidence of acetabular protrusion (AP) in OI and to evaluate the clinical consequences of this pelvic deformity. All 79 patients had iliac crest bone biopsy and pelvic radiographs. They were subdivided into OI type 1, 3, and 4, according to the Sillence classification, and type 5, according to Glorieux. AP was measured on pelvic radiographs… Expand
Pseudo-Protrusio Acetabular Deformity in Osteogenesis Imperfecta Patients.
It was showed that acetabular deformity is common in OI patients and is associated with disease severity, and superomedial bulging of the iliopectineal line was the most predictive radiographic sign. Expand
Acetabular Protrusion in a Cohort of Patients with Osteogenesis Imperfecta Evaluated in a Pediatric Hospital
The presence of AP was associated with the severity of the OI and age, and in a negative association with the ambulatory status, and a significant increase in the number of children with abnormal CE angles even in those with mild forms of OI. Expand
Acetabular Protrusio in Patients With Osteogenesis Imperfecta: Risk Factors and Progression.
The findings suggest AP may develop over time in patients with OI and may be influenced by patient factors such as age, sex, and BMI. Expand
Acetabular Protrusio and Proximal Femur Fractures in Patients With Osteogenesis Imperfecta
In this series of 49 OI patients, the overall incidence of acetabular protrusio was 55.1% with the highest incidence among patients with type III OI (70.6%), and patients with AP have an increased risk for proximal femur fractures and particularly femoral neck fractures. Expand
Pauwels Osteotomy for Femoral Neck Nonunion in Two Adult Siblings with Osteogenesis Imperfecta
This is a retrospective review of two adult siblings with osteogenesis imperfecta (OI) type III (according to Sillence classification), who sustained a spontaneous femoral neck fracture and subsequent nonunion, which resulted in healing despite compromised bone quality and limited bone stock. Expand
High Prevalence of Coxa Vara in Patients With Severe Osteogenesis Imperfecta
In conclusion, coxa vara in OI is not rare, especially in severe forms of the disease, and regular clinical and radiologic follow-up is indicated in children with previous femoral rodding and in severely affected children, particularly those with OI type III. Expand
The Hip in Osteogenesis Imperfecta
This chapter describes the clinical presentations, pathophysiology and treatment of coxa vara, acetabular protrusion, developmental hip dislocation, proximal femoral fractures and deformity in children with OI. Expand
High-Dose Steroid-Induced Protrusio Acetabuli: A Case Report
The aim of presenting this case was to demonstrate that using high doses of corticosteroids which are not directly involved in etiological factors can cause secondary protrusio acetabuli, the first case seen in the literature for the first time. Expand
Osteogenesis Imperfecta: Update on presentation and management
Cyclical intravenous pamidronate is now the standard of care for moderately to severely affected children with OI, given in combination with good orthopedic, physiotherapy and rehabilitation programs. Expand
Osteogenesis Imperfecta: A Case-Based Guide to Surgical Decision-Making and Care
Decision-Making and Surgical Principles After a thorough multidisciplinary analysis and optimal medical management, surgical treatment serves to realign and stabilize deformed and weakened bones.Expand


OSTEOGENESIS IMPERFECTA: An Orthopaedic Description and Surgical Review
Patients with osteogenesis imperfecta compensated for their disability by reasonable academic achievement and by choosing a sedentary occupation, and were able to walk, with or without assistance. Expand
Evaluation of the measurement methods for protrusio acetabuli in normal children
It is concluded that the most trustworthy method available to evaluate PA in children should be “line crossing”, provided that the ilioischial line is 1 or 3 mm or more for boys and girls, respectively. Expand
Obstruction of the colon due to protrusio acetabuli in osteogenesis imperfecta: treatment by pelvic osteotomy. Report of a case.
To correct deformities in both femora and both humeri, genita had corrective osteotomies, stabilized with extensible intramedullary rods, and was hospitalized for fecal impaction when he was four years old. Expand
Gastrointestinal problems in patients who have type-III osteogenesis imperfecta.
Chronic constipation and recurrent abdominal pain are more frequent in patients who have osteogenesis imperfecta and acetabular protrusion than in those who do not have protrusion and may benefit from early attention to a bowel program and referral to a gastrointestinal specialist. Expand
Protrusio Acetabuli in Childhood
Tivo factors are thus necessary to establish the presence of this condition : a deepened acet-abulum and a femoral head displaced into the increased depth of the increaseddepth of the pelvis. Expand
Type V Osteogenesis Imperfecta: A New Form of Brittle Bone Disease
  • F. Glorieux, F. Rauch, +7 authors N. Bishop
  • Medicine
  • Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
  • 2000
OI type V is a new form of autosomal dominant OI, which does not appear to be associated with collagen type I mutations, and the genetic defect underlying this disease remains to be elucidated. Expand
Genetic heterogeneity in osteogenesis imperfecta.
An epidemiological and genetical study of osteogenesis imperfecta (OI) in Victoria, Australia confirmed that there are at least four distinct syndromes at present called OI. The largest group ofExpand
Cyclic administration of pamidronate in children with severe osteogenesis imperfecta.
In children with severe osteogenesis imperfecta, cyclic administration of intravenous pamidronate improved clinical outcomes, reduced bone resorption, and increased bone density. Expand
Acetabular protrusio
  • Evarts CMcC, ed. Surgery of the musculoskeletal system,
  • 1983
Osteogenesis imperfecta als seltene Ursache eines Megacolons