Acellular vascular grafts generated from collagen and elastin analogs.

@article{Kumar2013AcellularVG,
  title={Acellular vascular grafts generated from collagen and elastin analogs.},
  author={Vivek A Kumar and Jeffrey M Caves and Carolyn A. Haller and Erbin Dai and Liying Liu and Stephanie Grainger and Elliot L. Chaikof},
  journal={Acta biomaterialia},
  year={2013},
  volume={9 9},
  pages={
          8067-74
        }
}
Tissue-engineered vascular grafts require long fabrication times, in part due to the requirement of cells from a variety of cell sources to produce a robust, load-bearing extracellular matrix. Herein, we propose a design strategy for the fabrication of tubular conduits comprising collagen fiber networks and elastin-like protein polymers to mimic native tissue structure and function. Dense fibrillar collagen networks exhibited an ultimate tensile strength (UTS) of 0.71±0.06 MPa, strain to… CONTINUE READING
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