Acellular spinal cord scaffold seeded with bone marrow stromal cells protects tissue and promotes functional recovery in spinal cord-injured rats.

@article{Chen2014AcellularSC,
  title={Acellular spinal cord scaffold seeded with bone marrow stromal cells protects tissue and promotes functional recovery in spinal cord-injured rats.},
  author={Jian Chen and Zhongmin Zhang and Jinxia Liu and Rongping Zhou and Xiaochen Zheng and Tianyu Chen and Liang Wang and Minjun Huang and Chengliang Yang and Zhen Li and Cheng Yang and Xiaochun Bai and Dadi Jin},
  journal={Journal of neuroscience research},
  year={2014},
  volume={92 3},
  pages={
          307-17
        }
}
Therapy using scaffolds seeded with stem cells plays an important role in repair of spinal cord injury (SCI), with the transplanted cells differentiating into nerve cells to replace the lost tissue while releasing neurotrophic factors that contribute to repair following SCI and enhance the function of the damaged nervous system. The present study investigated the ability to extend the survival time of bone marrow stromal cells (BMSCs) to restore the damaged spinal cord and improve functional… CONTINUE READING
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