Accurately annotate compound effects of genetic variants using a context-sensitive framework

Abstract

In genomics, effectively identifying the biological effects of genetic variants is crucial. Current methods handle each variant independently, assuming that each variant acts in a context-free manner. However, variants within the same gene may interfere with each other, producing combinational (compound) rather than individual effects. In this work, we… (More)
DOI: 10.1093/nar/gkx041

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Cite this paper

@inproceedings{Cheng2017AccuratelyAC, title={Accurately annotate compound effects of genetic variants using a context-sensitive framework}, author={Si-Jin Cheng and Fang-yuan Shi and Huan Liu and Yang Ding and Shuai Jiang and Nan Liang and G. R. Gao}, booktitle={Nucleic acids research}, year={2017} }