Accurate registration of serial 3D MR brain images and its application to visualizing change in neurodegenerative disorders.

@article{Freeborough1996AccurateRO,
  title={Accurate registration of serial 3D MR brain images and its application to visualizing change in neurodegenerative disorders.},
  author={Peter A. Freeborough and Roger P. Woods and Nick C. Fox},
  journal={Journal of computer assisted tomography},
  year={1996},
  volume={20 6},
  pages={1012-22}
}
PURPOSE To propose and assess methods that permit the accurate and robust registration of serially acquired 3D MR scans and to demonstrate their application in neurodegenerative disorders. METHOD 3D T1-weighted brain images were obtained on two or more occasions from 10 normal subjects and 8 patients with neurodegenerative disorders (scan intervals 3-21 months). Variants of an automated registration procedure were compared according to the goodness and robustness of match in normal subjects… CONTINUE READING
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