Accurate prediction of drug-induced liver injury using stem cell-derived populations.

@article{Szkolnicka2014AccuratePO,
  title={Accurate prediction of drug-induced liver injury using stem cell-derived populations.},
  author={Dagmara Szkolnicka and Sarah L. Farnworth and Baltasar Lucendo-Villarin and Christopher W Storck and Wenli Zhou and John Peter Iredale and Oliver Flint and David C. Hay},
  journal={Stem cells translational medicine},
  year={2014},
  volume={3 2},
  pages={141-8}
}
Despite major progress in the knowledge and management of human liver injury, there are millions of people suffering from chronic liver disease. Currently, the only cure for end-stage liver disease is orthotopic liver transplantation; however, this approach is severely limited by organ donation. Alternative approaches to restoring liver function have therefore been pursued, including the use of somatic and stem cell populations. Although such approaches are essential in developing scalable… CONTINUE READING