Accurate mass precursor ion data and tandem mass spectrometry identify a class I human leukocyte antigen A*0201-presented peptide originating from vaccinia virus.

@article{Johnson2005AccurateMP,
  title={Accurate mass precursor ion data and tandem mass spectrometry identify a class I human leukocyte antigen A*0201-presented peptide originating from vaccinia virus.},
  author={K. L. Johnson and Inna G. Ovsyannikova and Benjamin J. Madden and Gregory A. Poland and David C Muddiman},
  journal={Journal of the American Society for Mass Spectrometry},
  year={2005},
  volume={16 11},
  pages={1812-7}
}
We have used accurate mass precursor ion data generated on a hybrid linear-ion trap-Fourier transform ion cyclotron resonance mass spectrometer to augment tandem mass spectrometry (MS/MS) data generated on two different instrument types. Results from these experiments have allowed us for the first time to identify a naturally processed peptide presented by a class I human leukocyte antigen allele (HLA-A*0201) that was isolated from B cells infected by live vaccinia, the viral agent of the… CONTINUE READING

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