Accurate identification of non-polyadenylated RNA using a custom human cytomegalovirus tiling array.


Most eukaryotes regulate commonly translation by polyadenylation of messenger RNA. RNA sequences without 3' polyadenylation are usually quickly degraded, thus finely tuning the expression of gene transcripts. Some viruses are known to regulate mRNA levels via polyadenylation. A method is described that utilizes a customized tiling array to determine if any… (More)
DOI: 10.1016/j.jviromet.2012.09.020


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