Accuracy of traditional and novel serology tests for predicting cross-protection in foot-and-mouth disease vaccinated cattle.

@article{Brito2014AccuracyOT,
  title={Accuracy of traditional and novel serology tests for predicting cross-protection in foot-and-mouth disease vaccinated cattle.},
  author={Barbara Brito and Andr{\'e}s Maximiliano Perez and Alejandra Victoria Capozzo},
  journal={Vaccine},
  year={2014},
  volume={32 4},
  pages={433-6}
}
Foot-and-mouth disease virus (FMDV) antigenic-match between vaccine and field viruses has traditionally been estimated in vitro by computing the r1 value using virus neutralization test (VNT) or ELISA titers. In this study we compared the accuracy in predicting cross-protection between the r1 value estimated by VNT and two recently developed tests that measure IgG subtypes and avidity. Data analyzed consisted of 64 serum samples from FMDV A24/Cruzeiro vaccinated bovines challenged with the… CONTINUE READING