Accuracy of a continuous noninvasive hemoglobin monitor in intensive care unit patients*

  title={Accuracy of a continuous noninvasive hemoglobin monitor in intensive care unit patients*},
  author={Denis Frasca and Claire Dahyot-fizelier and Karen Catherine and Quentin Levrat and Bertrand Debaene and Olivier Mimoz},
  journal={Critical Care Medicine},
Objective:To determine whether noninvasive hemoglobin measurement by Pulse CO-Oximetry could provide clinically acceptable absolute and trend accuracy in critically ill patients, compared to other invasive methods of hemoglobin assessment available at bedside and the gold standard, the laboratory analyzer. Design:Prospective study. Setting:Surgical intensive care unit of a university teaching hospital. Patients:Sixty-two patients continuously monitored with Pulse CO-Oximetry (Masimo Radical-7… 
The Clinical Utility of Noninvasive Pulse Co-oximetry Hemoglobin Measurements in Dark-Skinned Critically Ill Patients
Noninvasive Hemoglobin measurement is a promising tool in dark-skinned critically ill patients with low hemoglobin levels, but requires further refinements for it to have clinical usefulness.
Evaluation of Noninvasive Hemoglobin Monitoring in Surgical Critical Care Patients*
Noninvasive hemoglobin monitoring performs most poorly in the lower hemoglobin ranges that include commonly used transfusion trigger thresholds and is not consistent within individual patients.
Accuracy of Noninvasive and Continuous Hemoglobin Measurement by Pulse Co-Oximetry During Preoperative Phlebotomy
Although the device provided a clinically acceptable correlation with the actual hemoglobin value and offers the value of a continuous trend monitor, given the precision of the device, it does not appear that actual transfusion decisions can be based on the device alone.
Research article Invasive versus noninvasive hemoglobin measurement by pulse CO-Oximeter in neonates admitted to NICU
Masimo Rainbow SET, Pulse CO‐oximetry developed by Masimo Corporation leverages 7 wavelengths and advanced signal processing technique to measure total haemoglobin (SpHb) values and improves quality of care in babies by non invasive way.
Accuracy of haemoglobin estimation by non-invasive Pulse Co-oximetry method : A prospective observational study among Neonates , Children and Young Adults
This study demonstrates that non-invasive pulse co-oximetry based haemoglobin estimation method (SpHb) is feasible in clinical setup and can generate comparable values to that of invasive laboratory-based auto-analyzer method of haemochemistry estimation (IHb).
Validation of a non-invasive pulse CO-oximetry based hemoglobin estimation in normal blood donors.
  • M. Al-Khabori, A. Al-Riyami, S. Daar
  • Medicine
    Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis
  • 2014
Accuracy and trending ability of hemoglobin measurement by the Pulse CO-Oximeter during vascular surgery
The results have shown that the SpHb is not precise enough to replace an invasive approach, but the trending ability of SpHB is accurate and may provide important information on the changes in hemoglobin concentration to guide blood management.
Validation of noninvasive hemoglobin measurement by pulse co-oximeter in newborn infants
The results suggest that noninvasive SpHb may be considered as an adjunct to invasive tHb measurements in newborn infants <3000 g especially in preterm infants ⩽32 weeks of gestation.
The relative trending accuracy of noninvasive continuous hemoglobin monitoring during hemodialysis in critically ill patients
The results of the current study indicate that SpHb measurement with the pulse CO-Oximeter has good relative trending accuracy.
Validation of continuous and noninvasive hemoglobin monitoring by pulse CO-oximetry in Japanese surgical patients
The strongest correlation between SpHB and tHb values was observed in patients with adequate peripheral perfusion suggesting that low perfusion may affect the accuracy of SpHb monitoring.


The Accuracy of Noninvasive and Continuous Total Hemoglobin Measurement by Pulse CO-Oximetry in Human Subjects Undergoing Hemodilution
Evaluated the accuracy of SpHb compared with laboratory CO-Oximeter measurement of tHb from arterial blood samples in 20 healthy volunteer subjects undergoing hemodilution, finding that Pulse CO- Oximetry–based Sphb measurement is accurate within 1.0 g/dL (1 SD) compared with Laboratory CO- oximeter tHB measurement in subjects undergoingHemodilutions.
Reliability of the HemoCue® hemoglobinometer in critically ill patients
Capillary HemoCue® is not sufficiently accurate to make a therapeutic decision such as whether a blood transfusion should be performed, but the method's performance was moderately improved by the use of arterial blood.
[Precision and accuracy of the immediate determination of hemoglobin using HemoCueB Hemoglobin in urgent, surgical, and critical patients].
Hb concentrations determined with the portable HBH analyzer may be highly useful for point-of-care monitoring of anemia and evaluating the transfusion requirements of ER, PRU, and ICU patients, however, the degree of inaccuracy and variability of Hb measurements in capillary blood samples would discourage us from using it in these patients.
Point of care hematocrit and hemoglobin in cardiac surgery: a review
It appears that the only accurate, consistent and reliable method to determine hemodilution and establish transfusion thresholds based on nadir hematocrits during cardiopulmonary bypass, and immediately post cardiac surgery, is with the use of co-oximetry.
Hemoximetry as the “Gold Standard”? Error Assessment Based on Differences Among Identical Blood Gas Analyzer Devices of Five Manufacturers
The variance of sO2 measurements between identical devices increased significantly when saturation decreased from the normal level of 97% to the hypoxemic levels of 85% and 75%.
HemoCue®, an Accurate Bedside Method of Hemoglobin Measurement?
Although the mean bias between HbCOOX and HbHC was relatively low, Hb measurement by HemoCue® exhibited a significant variability, andLoading multiple microcuvettes and averaging the results may increase the accuracy of Hb Measurement by HemiCue®,.
The CRIT Study: Anemia and blood transfusion in the critically ill—Current clinical practice in the United States*
The number of RBC transfusions a patient received during the study was independently associated with longer ICU and hospital lengths of stay and an increase in mortality and a nadir hemoglobin level of <9 g/dL was a predictor of increased mortality and length of stay.
Reliability of HemoCue in patients with gastrointestinal bleeding
Although it demonstrated a low bias between HemoCue and blood hemoglobin determination, large HemoHemoCue vs. hemoglobin differences may still occur, and therefore therapeutic decisions based upon capillary HemOCue alone should be very cautious.
Anemia, blood loss, and blood transfusions in North American children in the intensive care unit.
It is imperative to minimize blood loss from blood draws and to set clear transfusion thresholds to understand anemia development, blood loss, and red blood cell (RBC) transfusions in the pediatric intensive care unit (PICU).
Important role of nondiagnostic blood loss and blunted erythropoietic response in the anemia of medical intensive care patients*
Anemia is frequent and results in a high requirement for red blood cell transfusions in the medical intensive care setting, probably as a consequence of an inappropriate increase in erythropoietin production and diminished iron availability.